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However, follow-up studies indicate that nearly 10% of individuals treated with ESAs develop resistance, a condition often linked to iron deficiency and systemic inflammation (van der Putten et al., 2008

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In aging-related PD, the number of mitochondrial-lysosomal contacts decreases, and the instability of these contact sites leads to disruption of mitochondrial and lysosomal amino acid homeostasis

In conclusion, C0 and TH are of great importance in neonate birth weight, and routine examination of C0 and TH in the second trimester has a positive effect on the intervention of birth weight