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Deficiencies in B12 can directly lead to nerve damage and worsen symptoms of diabetic neuropathy.65 While most people can get adequate B12 through diet (meat, fish, dairy, fortified cereals), certain medications including metformin and proton pump inhibitors can impair absorption and raise the risk of deficiency

Common Side Effects Gastrointestinal effects: Nausea, stomach upset, and related GI symptoms are the most common

Ferreira et al., 2021