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Additionally, -synuclein disrupts lysosomes and mitochondria, promoting inflammasome activation

447,448 In postmortem samples of patients who committed suicide due to MDD, the expression of DNA methyltransferases (DNMTs) in the frontopolar cortex was found to be more significantly increased in women than in men

In a very practical sense, B12 and other water-soluble vitamins are the safest and easiest nutrients to supplement because your body takes what it needs and gets rid of what it doesnt

For those with MTHFR, L-methylfolate is the only way to bypass the MTHFR mutation and support healthy folate levels

Because glutathione plays an important role in cellular protection, lower levels are often discussed in relation to healthy ageing and vitality