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Neuropathological studies have provided evidence of increased dendritic spine density and aberrant dendritic spine morphology in individuals with ASD

For most but not all studies HEK and MDCK cells were serum starved for 24 hours prior to the initiation of drug treatment

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Human data is still very limited, including small pilot work such as the knee pain survey of 16 patients, plus a few other early studies and reviews calling out the lack of large, rigorous trials

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