A new human selenium-containing protein
Quercetin, luteolin, and apigenin can prevent NLRP3 inflammasome assembly, activate caspase-1, and cleave Gasdermin D (GSDMD) through reactive oxygen species (ROS) scavenging or Nrf2/HO-1 activation, thereby decreasing IL-1 secretion, inhibiting macrophage pyroptosis, and suppressing macrophage-driven inflammation (9496)
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But some ingredients, especially in skin-lightening products, hair dyes, fragrance-heavy formulas, adhesives, and brightening treatments, can damage melanocytes in susceptible individuals
Mol Cell Proteomics