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Pck1 is a key enzyme involved in gluconeogenesis from amino acids and pyruvate, while G6pc participates in gluconeogenesis from glycerol as well as from amino acids and pyruvate

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In a 2015 review in BioMed Research International , Pickart, Vasquez-Soltero and Margolina collated Connectivity Map data showing GHK modulates expression of roughly 31 percent of profiled human genes in cultured fibroblasts