BBB permeability assessments, like Fluorescein isothiocyanate (FITC) permeability assay and detection of edema using a MRI scan, are frequently performed in toxin-based animal models and suggest that MPTP or 6-OHDA exposure leads to increased leakage [232,233,234,235]
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Peptides affecting similar pathways may produce diminishing returns rather than synergy
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