how many mg of l-carnitine for weight loss Effects supplementation on and body composition: A systematic review and meta-analysis of 37 randomized controlled clinical trials with dose-response analysis L-Carnitine 3,000mg by EC Sports

Kishi S, Nagasu H, Kidokoro K, Kashihara N

3.4.1 Oxidative stress-endocrine axis integration ROS accumulation triggers activation of stress-activated protein kinases (JNK/p38 pathway), which subsequently inhibits AR transcriptional activity, creating a cascade that disrupts testosterone synthesis ( 3.4.2 Metabolism-immune-epigenetic crosstalk Inflammatory mediators including TNF- and NF-B activation modulate AR signaling capacity while IL-6 triggers DNA methylation changes that affect spermatogenesis ( 3.5 Emerging epigenetic mechanisms Recent investigations have revealed the critical role of non-coding RNAs and chromatin modifications in mediating EED-induced reproductive toxicity, providing new insights into both immediate and transgenerational effects

doi:10.1111/joim.12328 Zhou X, Jin M, Liu L, et al

The effect of (L-)carnitine on weight loss in adults: a systematic review and meta-analysis of randomized controlled trials. Obesity reviews : an official journal of the International Association for the Study of Obesity 17,10 (2016): 970-6

If I sleep on my left side I dont hear it and if I turn my head to extreme right I dont hear it either so Im guessing its to do with position of arteries