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Human research is limited, though animal data is robust and consistent across multiple models

A vitamin B12 deficiency occurs when your body does not have enough healthy red blood cells

While there is little research, anecdotal reports have found that taking vitamin B12 supplements before and after drinking alcohol can help replenish lost nutrients to recover more quickly from hangover symptoms

But the research didn't stop there

For patients diagnosed with a vitamin B12 deficiencyespecially when caused by problems with absorption in the digestive tract (such as pernicious anemia, certain gastrointestinal conditions, or after specific surgeries)oral supplements may not be effective