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doi: 10.1097/MD.0000000000021488 94 JanoutovJ.KovalovM.MachaczkaO.AmbrozP.ZatloukalovA.NmekK.et al

In the HOPE study, supplementation of 400 IU (=268 mg) of vitamin E/day in mild to moderate CKD patients has no effect on cardiovascular outcomes and overall mortality and therefore supplementation of vitamin E is not recommended (HOPE Study Investigators, 2000)

Despite these advances and their significant therapeutic potential, the molecular mechanisms underlying the potent cytoprotective effects of BPC157 remain largely undefined, limiting its full clinical translation

Sanchez-Cespedes M, Parrella P, Nomoto S, Cohen D, Xiao Y, Esteller M et al

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