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For example, the blood pressure-lowering effect of crocin is comparable to the well-known effect of losartan which decreases blood pressure by antagonizing the angiotensin II receptor

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J Biol Chem 270:14811484 Ursini F, Maiorino M, Brigelius-Flohe R, Aumann KD, Roveri A, Schomburg D, Flohe L (1995) Diversity of glutathione peroxidases