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Elevated fatty acids (FAs) activate Toll-like receptors (TLRs) in macrophages, which act in synergy with MSU crystals to trigger NLRP3 inflammasome activation and pro-inflammatory cytokine release (e.g., IL-1), thereby initiating the inflammatory cascade

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Study of the efficacy and tolerability of L-acetylcarnitine therapy in the senile brain

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Avidin:biotin interactions are so strong that elution of biotin-tagged proteins from avidin-conjugated resins usually requires denaturing conditions