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Furthermore, other anti-amyloid drugs such as Solanezumab that target monomeric A mirror such findings of apparently lowered A plaque levels, yet also disappointingly do not slow down cognitive decline (Sperling et al., 2023), a finding that is reflected in the many failed A centric AD treatments to date (Espay et al., 2023)

diabetes, cardiovascular and neurodegenerative diseases, metabolic syndrome, which includes obesity, some cancers and lower mortality