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doi: 10.1017/S0007114508998305 223 ChintalaSTthKCaoSDurraniFAVaughanMMJensenRLet al

In contrast, MCD leads to severe deficiency of methionine and choline, disrupting phosphatidylcholine synthesis, VLDL secretion, and mitochondrial respiration, which rapidly induces inflammation and liver damage

376 Similar to systemic IR, brain IR can be defined as failed response to insulin by brain cells, 377,378 primarily due to downregulated insulin receptors, an inability of insulin receptors to bind insulin, or dysfunction of the insulin signaling cascade

Long-COVID and Post-COVID health complications: an up-to-date review on clinical conditions and their possible molecular mechanisms

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