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Even though lesions persisted relatively unchanged in 16% of the patients, they still reported some alleviation in symptoms, suggesting that ozone therapy might be an effective alternative to more invasive interventions, such as bone ablation surgery, particularly for bisphosphonate-induced related jaw osteonecrosis cases [51]

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Sericin injection was given on the 3 rd and 6 th days by intratendinous injection (0.8 g/kg/mL), and DS was administered for 14 days by oral gavage (1.1 mg/kg/day)