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5-Amino-1MQ inhibits the NNMT enzyme to theoretically raise NAD+ levels and improve insulin sensitivity, but evidence is limited to preclinical animal studies only

Serious but less common risks may include: hypersensitivity reactions, hypokalemia (rare, with B12 correction of severe deficiency), and exacerbation of polycythemia

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These additives can affect the pH and osmolality of the solution, which influences injection site comfort