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For example, if a patient has a severe deficiency with malabsorption (unable to absorb vitamins from the gut) or is experiencing vomiting that prevents oral intake, an injection ensures the vitamin B is delivered into the body

Inadequate secretion of intrinsic factor, resulting from lesions that destroy the gastric mucosa (ingestion of corrosives, extensive neoplasia), and a number of conditions associated with a variable degree of gastric atrophy (such as multiple sclerosis, certain endocrine disorders, iron deficiency, and subtotal gastrectomy)

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