As reported by Glossy, NAD has had a meteoric rise in popularity over the past year, including IV drips and shots offered in wellness clinics and doctor offices, as well as ancillary at-home products, like precursor supplements (called NAD+), nasal spray, transdermal patches and skin care
Metformin, the first-line oral glucose-lowering agent recommended by NICE for type 2 diabetes (NG28), is well established as a cause of B12 malabsorption
Unlike many anti-aging active ingredients, such as retinoids, copper peptides tend to be well tolerated and non-irritating to the skin, which makes them popular in cosmetics
10.1172/jci72316 J
And the side effects of remaining B12 deficient are potentially far worse (at best, living a half life - on a good day)