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doi: 10.1038/s42003-021-01876-x 39 LiangJCaoRWangXZhangYWangPGaoHet al

Why is AOD-9604 supplied as a lyophilized powder rather than a pre-mixed solution

There are a total of 27 claudins in mammals, although not all claudins have relevance for the intestinal barrier [19]

When evaluated in HEK293 cells with URAT1 overexpression, digalic acid showed an IC 50 of 5.34 M, with an intermediate value between the two positive controls, benzobromarone and lesinurad

While it is not classified as a controlled substance, it is also not approved by any major regulatory agencyincluding the FDA , EMA , or TGA for human use