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After 28 days, bacterial growth risk increases even with the benzyl alcohol preservative, and peptide degradation may begin to affect results

A study by Gameiro et al

Central to this approach are dose modification protocols guided by the Common Terminology Criteria for Adverse Events (CTCAE), which provide standardized thresholds for adjusting or withholding treatment based on toxicity grade

Funding This work was supported by grants from the National Natural Science Foundation of China (NSFC Numbers 81672800, 81603009, 81673020, 81802632, and 82173830), Natural Science Foundation of Shaanxi (2020JQ-445), and the Key Research and Development Program of Shaanxi Province (2021SF-207, 2021SF-223, and 2022ZDLSF05-19)

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