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It will be interesting to determine whether aging increases DNA methylation of astrocyte-secreted Wnt factors, which might explain the lower rate of neurogenesis in old brain (Zhao et al., 2008) and the observation that early postnatal astrocytes are more efficient in promoting the in vitro neuronal differentiation of NPCs than astrocytes derived from the adult brain (Song et al., 2002)

The research on PQQ is still in early stages, and most of studies so far have been done on animals

Peptides are short chains of amino acids that act as messengers within the body

Detecting oxidative modification of biomolecules with isotope dilution mass spectrometry: sensitive and quantitative assays for oxidized amino acids in proteins and tissues

Inhibition of Rac1 activity in the hippocampus impairs the forgetting of contextual fear memory