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The association between PM2.5 and heart and lung health effects is well documented in scientific literature

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however, it is unknown whether this is due to people with healthier brain dopaminergic reward centers (the area of the brain affected by Parkinson's) being more likely to enjoy smoking and thus pick up the habit, nicotine directly acting as a neuroprotective agent, or other compounds in cigarette smoke acting as neuroprotective agents

The study identified data from 59 countries and included over 10,000 data points collected from over 600 published articles

Beginning July 1, 2019, Illinois law prohibits the sale of tobacco products, including these products, to people younger than age 21