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Mechanism and gene expression Pickart and colleagues used Broad Institute Connectivity Map data to show GHK-Cu modulates expression of more than 4,000 human genes, with shifts toward patterns associated with younger tissue

5-Methoxyflavone-induced AMPK activation inhibits NF-B and P38 MAPK signaling to attenuate influenza A virus-mediated inflammation and lung injury in vitro and in vivo

ET-1, a vasoconstrictor peptide originating from endothelial cells, exerts its effects through endothelin receptors and is correlated with cardiovascular disease severity

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Rebholz H, Friedman E, Castello J