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A recent study demonstrated that cystine deprivation can reduce the expression of GPX4 by preventing mTORC1/eukaryotic translation initiation factor 4E-binding protein 1-mediated protein repression (109)

The use of exogenous antioxidants in the prevention and treatment of diseases Therapeutic applications of antioxidants have advanced significantly, with strategies increasingly targeting intracellular bioactivity, particularly mitochondrial protection and modulation of redox pathways

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