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Side Effects and Safety Both AOD 9604 and Semaglutide are generally considered safe, but they have different side effect profiles: AOD 9604 : This peptide has minimal reported side effects in clinical studies, making it a safer option for individuals who are sensitive to traditional growth hormone therapy

Phase 3 trials show Mazdutide reduces liver fat by 80.2% in NASH patients

Some patients may benefit from cycling the treatment (e.g., 5 days on, 2 days off) or adjusting injection timing for better results

A 2025 intravenous safety study involving two healthy adults found infusions up to 20 mg well tolerated, with no adverse events or clinically meaningful changes in vital signs or laboratory biomarkers

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