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2.1 LC3 adaptor protein and ubiquitin-dependent pathway Currently, research has identified five LC3 adaptor proteins, including sequestosome-1 (SQSTM1/P62), optineurin (OPTN), nuclear dot protein 52 (NDP52), TAX1 binding protein 1 (TAX1BP1), and neighbor of breast cancer susceptibility gene one protein (NBR1) (Stolz et al., 2014) (Figure 1A)

Another animation by AIM available at about the tobacco withdrawal cycle, might be a useful tool when explaining links between tobacco use and depression/anxiety symptoms to patients

Br Dent J 189 , 352354 (2000)

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