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Li et al., 2022b)

NQO1 metabolizing benzene, quinones, air pollution NAT1 and NAT2 N-acetyltransferases, cigarette smoke, hydrocarbons COMT adds methyl groups to modify endogenous substances, including estrogen, for elimination Elimination: Phase III Transporter Proteins Phase I and Phase II happen inside your cells, but once a metabolite has been made water-soluble, it still has to physically leave the cell and then the body

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S -nitrosylation, the covalent attachment of an NO moiety to a reactive cysteine thiol to form an SNO, has emerged as a prototypic redox-mediated modification in plants