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Symptoms and Methods of Assessment of Brain/Mental Fatigue and Brain Energy Brain fatigue cannot be adequately diagnosed with blood tests, cognitive tests, or brain imaging techniques since the underlying cause of brain fatigue in the individual patient should be clarified and a direct temporal relationship with illness or damage to the nervous system [5,95]

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F-Actin Stabilization: At a cellular level, it influences the formation of focal adhesions by stabilizing F-actin proteins, crucial for structural cellular integrity during migration across damaged extracellular matrices 6