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Thus, pseudotripeptides 45 and 46 exhibit Ki values of 2 and 4 nM, respectively and an approximately 10-fold selectivity vs

The motif scan analysis revealed that SmGST consists of a casein kinase II phosphorylation site (9295) and a protein kinase C phosphorylation site (9294)

In AD, however, tau undergoes pathological hyperphosphorylation, leading to its dissociation from microtubules, aggregation into neurofibrillary tangles, and ultimately neuronal dysfunction ( Iron overload is hypothesized to exacerbate this process through several pathways

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