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Phenylbutyrate is an HDAC inhibitor (similar action to butyrate from microbes) and TUDCA is a bile acid that can modulate gut microbiota composition as well as reduce ER stress in neurons [225]

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It hosts an exceptionally dense microbial population (10 11 cells/mL), dominated by bacteria but also including archaea, protozoa, and anaerobic fungi, a composition distinct from monogastric systems (Table 1)

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