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Gastrointest Endosc

Ultimately, advancements in these areas will determine whether probiotics and related live biotherapeutics can transition from broadly categorized health-promoting supplements to precisely targeted, mechanism-based interventions that are incorporated into evidence-based guidelines for both prevention and treatment (294)

114 Furthermore, lactylation of c-myc, a downstream target of the Wnt/-catenin pathway, increases its protein stability and stemness, thereby facilitating HCC progression

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