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GHK-Cu doesn't directly block DHT (that's finasteride's job), but there's evidence it downregulates androgen receptor expression in follicular cells, potentially blunting the follicle's sensitivity to DHT

~ AlphaMD Jake was staring at the ceiling again at 3 a.m., wired and exhausted at the same time, wondering if starting TRT was worth it if he never slept again

The 2-AR for example is known to be phosphorylated by PKA on serine residues in the 3rd intracellular loop, and by GRKs on serine residues in the proximal COOH terminus of the GPCR (Yuan et al ., 1994