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These are distinguished by important differences in sugar, nicotine, and nitrogen content (Browne, 1990)

it seems that the true zeta-potential of TMVLys remains ambiguous as other studies have reported a surface charge of 60 and 14.5 mV, and there may have been differences in experimental procedures such as particle concentration and solutions (57, 58)

If prohibition no matter how toothless is off the table, there are still the array of policy interventions which fall under the umbrella of "prevention." These aim, through education and public awareness-raising, to discourage use of technically legal substances