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Palliyaguru DL, et al

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Berberine also reduces apoptosis by modulating the PI3K/Akt and p38-MAPK pathways ( Moreover, berberine promotes neurogenesis in the dentate gyrus after TBI by increasing the expression of Brain-derived neurotrophic factor (BDNF) (Suwannakot et al., 2022)

With regular use, youll likely see fewer fine lines, less sagging, and a smoother texture