Likewise, several other chemotherapeutic agents, such as platinum complexes (e.g., cisplatin) [194] and sorafenib [195], enhance mitochondrial ROS production or hinder the antioxidant system, thereby causing heightened ROS levels within cancer cells
[12] DSIP abundance has been observed to be lower in cerebrospinal fluid of research models of depression compared to the same controls
placebo on the time to occurrence of a composite cardiovascular outcome (nonfatal myocardial infarction, nonfatal stroke, cardiovascular death, hospitalization or urgent visit due to heart failure) and a composite renal outcome (end-stage kidney disease, 40% sustained decline in eGFR, cardiovascular death or renal death) in 10,000 individuals with atherosclerotic cardiovascular disease and/or CKD
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