Recombinant hCG was found to be more potent than LH in both HEK293 and mouse Leydig tumour cells, demonstrating that LH and hCG display biased agonism at their shared receptor
The brain receives satiety signals from two completely independent pathways
Limited Human Very few human clinical trials exist, and those that do are generally small-scale, preliminary investigations
For retrograde monosynaptic tracing of the PVN DMV circuit, the helper viruses containing rAAV-EF1-DIO-RVG-WPRE-hGH pA (AAV-DIO-RVG, AAV2/9, 4.59 10 12 vg/mL) and rAAV-EF1-DIO-H2B-mCherry-T2A-TVA-WPRE-hGH pA (AAV-DIO-TVA-mCherry, AAV2/9, 5.56 10 12 vg/mL) (1:2, 150 nL) were injected into the DMV, and scAAV2/Retro-hSyn-Cre-WPRE (20 L) was injected into the small intestinal wall of C57 mice
They can be utilized for the direct and indirect detection of antigens in various assays, as capture molecule immobilized on microplates, or as ligand for protein purification