Compounds that chelate free metal ions in a way that prevents them from generating free radicals offer promise in the treatment of neurodegenerative diseases and other chronic diseases in which metal-induced oxidative damage may play a pathogenic role (21)
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doi: 10.4103/1673-5374.332124
A comprehensive evaluation of various factors, including the dosage of the medication, the administration route, the specific type of hormonal agent utilized (whether combined estrogen or progestin), the timing of treatment initiation, the patients age, her cardiovascular disease history, and the thromboembolic characteristics associated with estrogen and progestin, is essential for postmenopausal hormone replacement therapy (171)