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Clinical trials have included both male and female participants, with some notable observations: Metabolic differences Men typically have higher baseline metabolic rates and different fat distribution patterns, which may influence response magnitude but not optimal dosing protocols

Studies have shown that the concentration of GHK in the plasma of a 20-year-old is around 200 g L 1 , but its levels tend to decrease with age, reducing the skins ability to regenerate [66]

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10 Among them, Wnt3a and Wnt1 act as ligands to activate the Wnt/-catenin signalling pathway after translation and modification