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Compared to radiation therapy, PDT and PTT can complement mainstay cancer treatments, overcome chemotherapy resistance, modify tumor perfusion, and vascular and extracellular matrix permeability, improve tumor drug delivery, provide greater spatiotemporal control, and lower the risk of secondary cancer development (Figure 2)

49 NakamichiI.TomitaY.ZhangB.SugiyamaH.KanakuraY.FukuharaS.et al (2007)