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In vitro, OGD-induced ferroptosis was ameliorated by GSH, which restored cell proliferation, reduced oxidative stress, and upregulated ferroptosis defense factors

106 Schizophrenia has also been associated with oxidative stress and reduced GSH levels in the brain

More than 5 billion people could suffer water shortages by 2050 due to climate change, increased demand and polluted supplies, according to a UN report on the state of the worlds water

DISCLOSURES: The authors report no conflicts of interest relevant to the content of this article

PMID: 41203627 Acta Pharmacol Sin Targeting PPAR activation sensitizes glioblastoma cells to temozolomide and reverses acquired resistance by inhibiting H3K18 lactylation