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Very high doses may potentially lower zinc levels or interact with certain medications, including chemotherapy and immunosuppressants

Pernicious anemia is a B12 deficiency anemia caused by the lack of intrinsic factor.[ref] What causes the lack of intrinsic factor in pernicious anemia

In in vitro fertilization: A randomized prospective controlled trial

Patients meeting the inclusion/exclusion criteria were randomized in a 2:1 ratio to receive a 2 mg dose of EGRIFTA (1 mg/vial formulation) or placebo subcutaneously daily for 26 weeks