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6a, right column) in vivo compared with its robust activity in cultured cells (Fig

Lin C, Chao H, Li Z, Xu X, Liu Y, Bao Z, et al

JAMA 311, 17701777

Cancer Cell 28 , 329342 (2015)

However, ascorbate accumulation was completely blocked in the D dhar pad2-1 quadruple mutants , which consistently showed bleaching, lower photochemical activity and a higher accumulation of threonate in response to high light