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In addition, Cross-trial caution: A 10% result in one trial is not necessarily weaker or stronger than an 11% result in another

Heliyon 5 (5), e01585

Figure 2 Although bacteria that produce SCFAs and SCFAs themselves confer advantages to human health, it is uncertain whether these effects are solely due to SCFAs alone or result from synergistic actions with other metabolites produced by these bacteria

Superoxide anions may directly react with NO, thereby stimulating the production of the NO/superoxide anion reaction product peroxynitrite (ONOO ), which in turn has been shown to uncouple the endothelial nitric oxide synthase (eNOS), thereby causing an anti-atherosclerotic NO-producing enzyme to become a ROS-producing enzyme, thus accelerating the atherosclerotic process

(2009) Celecoxib prevents tumor growth in an animal model by a COX-2 independent mechanism