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Aberrant redox signaling is widely recognized as a contributor to the development of diabetic complications, including DR and several pathological mechanisms contribute to the accumulation of reactive oxygen species (ROS) in diabetic wounds [8]

Conclusion Hypothyroidism can result in many undesirable symptoms like dry skin, chronic fatigue, memory loss, high cholesterol, and an increased risk of heart disease

Fatigue was evaluated by Wessely and Powell scores

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