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2004;24:255-275.doi:10.1146/annurev.nutr.23.011702.073054 Fraker PJ, King LE, Laakko T, VollmerTL

Mech Ageing Dev 190:111309 Tawfik A, Mohamed R, Kira D, Alhusban S, Al-Shabrawey M (2021) N-Methyl-D-aspartate receptor activation, novel mechanism of homocysteine-induced bloodretinal barrier dysfunction

The activation of JAK/STAT3 signaling, either stimulated by insulin/IGF-1 or cytokine signaling, is able to trigger the STAT3/SOCS/p53 pathway, thus promoting cellular senescence and immunosenescence (see above)

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GHSR-1a receptor selectivity enables targeted GH release by restricting ipamorelins activity to signaling pathways that specifically regulate somatotroph secretion