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Besides, ISL treatment not only effectively reduced TNF- and IL-6 gene expression in LPS-induced mouse primary peritoneal macrophages but also attenuated lung and liver injuries induced by LPS, accompanied by decreased inflammatory responses, which may be strongly related to NF-B inhibition (Yang et al., 2021b)

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BSO treatment was performed similarly as for ITCs by adding it (100 mM stock solution prepared in water) to the medium (either on its own or in combination with ITC) to obtain BSO concentrations ranging from 50 M to 700 M

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