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Many of these trials are constrained by limited sample sizes, brief follow-up periods, and variability in fasting protocols, which complicates direct comparisons among studies

1A) showed that with PLB treatment, the pathological structure of ovarian tissue showed significant improvement, including more normal follicular development and a reduction in cysts, indicating its protective effect on ovarian morphology

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Abstract Diabetic kidney disease (DKD) has emerged as the leading cause of chronic kidney disease (CKD) worldwide, surpassing primary glomerular disorders in prevalence

Additionally, peptide hormones interact with the gut microbiome to regulate the production of short-chain fatty acids, which are crucial for maintaining a healthy gut environment