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The time interval of examination depends on the presence of risk factors for the onset and worsening of DR such as uncontrolled hyperglycemia and diabetic macular edema

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Although researchers did not observe significant changes in body weight, body mass index (BMI), waist-to-hip ratio, lean body mass, or total body fat percentage, participants demonstrated improvements in several measures of muscle strength and muscular endurance (2)

One aspect that needs to be considered is that in these volunteer studies, patients are being fed an adequate diet during the trial

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