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(2) In NK cells, upregulation of inhibitory receptors NKG2A, TIM-3, Toll-like receptor 2 (TLR2), CD94, and PD-1, as well as decreased secretion of tumor necrosis factor- (TNF-) and interferon-gamma (IFN-), are all factors promoting the occurrence and development of HCC

Bravo-Veyrat S, Hopfgartner G