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Existing FDA-Approved Weight Loss Medications Several FDA-approved weight loss medications, including prescription weight loss medications, are already available, including: Orlistat Phentermine-topiramate Naltrexone-bupropion Liraglutide Semaglutide Tirzepatide These medications offer various mechanisms and benefits, helping individuals achieve significant weight loss and manage excess weight-related health conditions to treat obesity

Another option for vitamin B12 supply, which is given in particular in the case of a clinically manifest deficiency, is the parenteral form or vitamin B12 injections

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Moreover, tumours did not show signs of oxidative stress or compensatory metabolic changes, such as accumulation of cysteine (Extended Data Fig